The 1965 Galaxie was an all-new design, featuring vertically stacked dual headlights in what was becoming the fashionable style in a car somewhat taller and bulkier than the previous year's. The new top-of-the-line designation this year was the Galaxie 500 LTD. Engine choices were the same as 1964, except for an all-new 240 cu in (3.9 L) six-cylinder and 1965 289 cu in (4.7 L) engine replacing the 50s-era 223 "Mileage-Maker" six and the 352 being equipped with dual exhausts and a four-barrel carburetor.
Suspension on the 1965 models was dramatically redesigned. Replacing the former leaf-spring rear suspension was a new three-link system, featuring all coils. Not only did the ride improve, but handling also got a boost, and this system was used for NASCAR in the full-size class. Interiors were like the 1964 models, but a new instrument panel and two-way key system were introduced.